Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.70 |
| ▸ | PGR | P06401 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.70 |
| ▸ | AR | P10275 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24525578 | 1.00 | KDM4E (0.79) | KDM4EHIF1APGRLMNACYP3A4 | |
| SCHEMBL24852454 | 1.00 | KDM4E (0.79) | KDM4EHIF1APGRLMNACYP3A4 | |
| SCHEMBL5708123 | 1.00 | KDM4E (0.79) | KDM4EHIF1APGRLMNACYP3A4 | |
| SCHEMBL3170728 | 0.88 | KDM4E (1.00) | KDM4EHIF1APGRLMNACYP3A4 | |
| SCHEMBL3170744 | 0.88 | KDM4E (1.00) | KDM4EHIF1APGRLMNACYP3A4 | |
| SCHEMBL5259047 | 0.88 | KDM4E (1.00) | KDM4EHIF1APGRLMNACYP3A4 | |
| SCHEMBL3170735 | 0.88 | KDM4E (1.00) | KDM4EHIF1APGRLMNACYP3A4 | |
| SCHEMBL11368251 | 0.88 | KDM4E (0.63) | KDM4EHIF1APGRLMNACYP3A4 | |
| SCHEMBL6152790 | 0.86 | KDM4E (0.76) | KDM4EHIF1APGRLMNACYP3A4 | |
| SCHEMBL5943277 | 0.85 | KDM4E (0.80) | KDM4EHIF1APGRLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422235-B1 | STEREOSELECTIVE METHOD OF PRODUCING 6ALPHA-FLUOROPREGNANES AND INTERMEDIARIES | RAGACTIVES SL (ES) | 2006-10-04 | — | — | EP | disclosed |
| US-20040181055-A1 | Stereoselective process for the production of 6alpha-fluorpregnanes and intermediates | RAGACTIVES, S.L. | 2004-09-16 | — | — | US | disclosed |
| EP-1422235-A1 | STEREOSELECTIVE METHOD OF PRODUCING 6ALPHA-FLUOROPREGNANES AND INTERMEDIARIES | Ragactives, S.L. (ES) | 2004-05-26 | — | — | EP | disclosed |
| EP-0105650-B1 | PROCESS FOR PREPARING 9,11-EPOXY STEROIDS FROM 9 ALPHA-SUBSTITUTED-11-HYDROXY STEROIDS | THE UPJOHN COMPANY (US) | 1988-06-08 | — | — | EP | disclosed |
| US-4442035-A | Acyclic amine epoxide process | THE UPJOHN COMPANY (US) | 1984-04-10 | — | — | US | disclosed |
| US-4255331-A | 3-Acetoxy-9β-11β-epoxy-dienes and the preparation of the corresponding 6α-halogen-4-ene-3-ones | PROCHEM ESTABLISHMENT (LI) | 1981-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181055-A1 | Stereoselective process for the production of 6alpha-fluorpregnanes and intermediates | NR5A1, SRD5A2, SRD5A1 | KDM4E 1969/4885HIF1A 1830/4885PGR 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.