Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | PGR | P06401 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708123 | 0.88 | KDM4E (0.79) | KDM4EHIF1ALMNAPGRCYP3A4 | |
| SCHEMBL24525578 | 0.88 | KDM4E (0.79) | KDM4EHIF1ALMNAPGRCYP3A4 | |
| SCHEMBL5708128 | 0.88 | KDM4E (0.79) | KDM4EHIF1ALMNAPGRCYP3A4 | |
| SCHEMBL24852454 | 0.88 | KDM4E (0.79) | KDM4EHIF1ALMNAPGRCYP3A4 | |
| SCHEMBL11322898 | 0.86 | HIF1A (0.52) | KDM4EHIF1ALMNAPGRCYP3A4 | |
| SCHEMBL11322896 | 0.86 | HIF1A (0.52) | KDM4EHIF1ALMNAPGRCYP3A4 | |
| SCHEMBL11362338 | 0.84 | HIF1A (0.63) | KDM4EHIF1ALMNAPGRCYP3A4 | |
| SCHEMBL10937267 | 0.84 | HIF1A (0.63) | KDM4EHIF1ALMNAPGRCYP3A4 | |
| SCHEMBL32668997 | 0.84 | HIF1A (0.63) | KDM4EHIF1ALMNAPGRCYP3A4 | |
| SCHEMBL5708002 | 0.84 | HIF1A (0.63) | KDM4EHIF1ALMNAPGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029151-A2 | 6-Alpha-fluoro-9-alpha-chloro-prednisolone-17,21 diesters, pharmaceutical compositions containing them and intermediates | STEROSYNT Ltd. (GB) | 1981-05-27 | — | — | EP | disclosed |