Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825928 | 0.82 | PRKCA (0.32) | PRKCA | |
| SCHEMBL29826071 | 0.82 | PRKCA (0.32) | PRKCA | |
| SCHEMBL29825846 | 0.82 | PRKCA (0.32) | PRKCA | |
| SCHEMBL23530390 | 0.82 | PRKCA (0.32) | PRKCA | |
| SCHEMBL29825911 | 0.82 | PRKCA (0.32) | PRKCA | |
| SCHEMBL23530392 | 0.82 | PRKCA (0.32) | PRKCA | |
| SCHEMBL6149357 | 0.81 | PRKCA (0.41) | PRKCA | |
| SCHEMBL6050053 | 0.77 | PRKCA (0.40) | PRKCALMNAPTGER4PTGER3PTGER2 | |
| SCHEMBL2048950 | 0.77 | PRKCA (0.39) | PRKCAHIF1ALMNA | |
| SCHEMBL3674711 | 0.75 | PRKCA (0.32) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018238-A2 | BIODEGRADABLE ORIENTED POLYESTER FILM AND PREPARATION METHOD THEREOF | SKC CO., LTD. (KR) | 2012-02-09 | — | — | WO | disclosed |