Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 13/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 7/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 7/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708231 | 0.80 | CRBN (0.36) | MPOKDM1AKCNH2 | |
| SCHEMBL5708177 | 0.78 | NR3C1 (0.35) | MPO | |
| SCHEMBL3968483 | 0.75 | ADORA3 (0.43) | PARP1PARP2PARP3ADORA3NOTUM | |
| SCHEMBL3962929 | 0.73 | PARP1 (0.45) | PARP1PARP2PARP3ADORA3NOTUM | |
| SCHEMBL3968503 | 0.73 | NOTUM (0.43) | PARP1PARP2PARP3ADORA3NOTUM | |
| SCHEMBL3965152 | 0.72 | PPARD (0.57) | — | |
| SCHEMBL3961112 | 0.72 | PPARD (0.41) | PARP1 | |
| SCHEMBL3963602 | 0.72 | ADORA3 (0.40) | PARP1PARP2PARP3ADORA3NOTUM | |
| SCHEMBL5708193 | 0.72 | PARP1 (0.34) | PARP1PARP2PARP3ADORA3NOTUM | |
| SCHEMBL3966971 | 0.72 | PPARA (0.48) | PARP1PARP2PARP3ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706386-A1 | BICYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-10-04 | — | — | EP | claimed |
| WO-2005066136-A1 | BICYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-07-21 | — | — | WO | claimed |