Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708306 | 1.00 | MEN1 (0.41) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL23949295 | 0.83 | MAOA (0.46) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL570033 | 0.82 | MEN1 (0.50) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL5708384 | 0.81 | MEN1 (0.47) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL5708383 | 0.81 | MEN1 (0.47) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL3765616 | 0.81 | MEN1 (0.47) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL15297367 | 0.80 | SERPINE1 (0.39) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL15297382 | 0.80 | CYP2D6 (0.43) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL28097950 | 0.80 | MEN1 (0.46) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL15570371 | 0.80 | CYP2D6 (0.43) | MEN1GAAKMT2ATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008590-B1 | Process for preparing optically active oxazolidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2006-10-11 | — | — | EP | disclosed |
| US-6403804-B1 | ALLOWING HYDRAZINE TO REACT ON OPTICALLY ACTIVE ACID ESTER HAVING HYDROXYL GROUP AT 3-POSITION TO GIVE OPTICALLY ACTIVE HYDRAZIDE HAVING HYDROXYL GROUP AT 3-POSITION, SUBJECTING OPTICALLY ACTIVE HYDRAZIDE TO CURTIUS REARRANGEMENT | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1008590-A1 | Process for preparing optically active oxazolidinone derivative | Takasago International Corporation (JP) | 2000-06-14 | — | — | EP | disclosed |