SCHEMBL5708463

SCHEMBL5708463

O=C/C=C/c1ccc(O)cc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 2/20 0.59
CCND1 P24385 2/20 0.59
TYR P14679 3/20 0.55
SYNJ2 O15056 1/20 0.55
TTR P02766 1/20 0.55
CYP1A1 P04798 1/20 0.55
BCHE P06276 1/20 0.55
MMP2 P08253 1/20 0.55
ALOX5 P09917 1/20 0.55
PTPN1 P18031 1/20 0.55
PTGS1 P23219 1/20 0.55
CYP1B1 Q16678 1/20 0.55
PTPN22 Q9Y2R2 1/20 0.55
CHRNA7 P36544 7/20 0.53
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPT P10636 1/20 0.52
CCNB2 O95067 1/20 0.50
CDK1 P06493 1/20 0.50
CCNB1 P14635 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32679861 1.00 CDK4 (0.59) CDK4CCND1TYRSYNJ2TTR
SCHEMBL5708464 1.00 CDK4 (0.59) CDK4CCND1TYRSYNJ2TTR
SCHEMBL3437049 0.83 ALDH1A1 (0.59) CDK4CCND1ALOX5KDM4EALDH1A1
SCHEMBL3437050 0.83 ALDH1A1 (0.59) CDK4CCND1ALOX5KDM4EALDH1A1
SCHEMBL1822010 0.82 TYR (0.75) TYRSYNJ2TTRCYP1A1BCHE
SCHEMBL1822012 0.82 TYR (0.75) TYRSYNJ2TTRCYP1A1BCHE
SCHEMBL8746740 0.82 KDM4E (0.50) CDK4CCND1TYRSYNJ2TTR
SCHEMBL27384085 0.80 TYR (0.59) TYRSYNJ2TTRCYP1A1BCHE
SCHEMBL20292376 0.80 CDK4 (0.55) CDK4CCND1KDM4EALDH1A1MAPT
SCHEMBL7855651 0.80 KDM4E (0.48) CDK4CCND1TTRCHRNA7KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235549-B1 AGENT FOR COLOURING KERATIN CONTAINING FIBRES HENKEL KGAA (DE) 2006-11-29 EP claimed
EP-1292268-B1 AGENT FOR DYEING KERATIN CONTAINING FIBERS HENKEL KGAA (DE) 2005-02-23 EP claimed
EP-1292269-B1 AGENT FOR DYEING KERATIN CONTAINING FIBERS HENKEL KGAA (DE) 2005-02-09 EP claimed
US-6790239-B1 COMBINATION OF AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-09-14 US claimed
US-6956013-B2 Photo-activated pro-fragrances THE PROCTER & GAMBLE COMPANY (US) 2005-10-18 US disclosed
US-6790239-B1 COMBINATION OF AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-09-14 US disclosed
US-20040087454-A1 Photo-activated pro-fragrances PROCTER & GAMBLE COMPANY, THE 2004-05-06 US disclosed
US-20030004072-A1 Photo-activated pro-fragrances THE PROCTER & GAMBLE COMPANY 2003-01-02 US disclosed