Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708497 | 0.74 | SMN1; SMN2 (0.38) | MAPK1HTTNPC1TP53RAB9A | |
| SCHEMBL5708484 | 0.74 | LMNA (0.48) | MAPK1HTTNPC1TP53RAB9A | |
| SCHEMBL5708491 | 0.70 | MAPT (0.44) | MAPK1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5708482 | 0.69 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4615529 | 0.69 | — | — | |
| SCHEMBL4616268 | 0.63 | MAPK1 (0.46) | MAPK1HTTNPC1TP53RAB9A | |
| SCHEMBL4616271 | 0.63 | MAPK1 (0.46) | MAPK1HTTNPC1TP53RAB9A | |
| SCHEMBL9303727 | 0.60 | NPC1 (0.33) | MAPK1HTTNPC1TP53RAB9A | |
| SCHEMBL17107186 | 0.60 | RAB9A (1.00) | MAPK1HTTNPC1TP53RAB9A | |
| SCHEMBL5708516 | 0.59 | CNR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599179-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | claimed |
| EP-1599179-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | disclosed |
| EP-1599179-A1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004078153-A1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-09-16 | — | — | WO | disclosed |