SCHEMBL5708928

SCHEMBL5708928

COC1NCCc2ccccc21.COc1ccccc1CCN

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.55
OPRM1 P35372 2/20 0.43
GID4 Q8IVV7 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
PRCP P42785 2/20 0.39
HTR2A P28223 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL327054 0.80 PRCP (0.56) OPRM1GID4MEN1KMT2APRCP
SCHEMBL31062461 0.80 PRCP (0.56) OPRM1GID4MEN1KMT2APRCP
Hydrochloric Acid SCHEMBL2771890 0.79 PRCP (0.54) TAAR1OPRM1GID4MEN1KMT2A
SCHEMBL8552878 0.75 PRCP (0.58) OPRM1GID4PRCP
SCHEMBL29350784 0.74 TAAR1 (1.00) TAAR1
SCHEMBL305943 0.74 TAAR1 (1.00) TAAR1
Iodide SCHEMBL28805523 0.72 TAAR1 (0.96) TAAR1
Hydrochloric Acid SCHEMBL11152248 0.72 TAAR1 (0.96) TAAR1
SCHEMBL1038233 0.72 GID4 (0.45) OPRM1GID4PRCPHTR2A
SCHEMBL2796297 0.70 GID4 (0.63) OPRM1GID4MEN1KMT2APRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1708999-A1 BRONCHORELAXING COMPOUNDS RESPIRATORIUS AB (SE) 2006-10-11 EP disclosed
WO-2005070887-A1 BRONCHORELAXING COMPOUNDS RESPIRATORIUS AB (SE) 2005-08-04 WO disclosed