Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630965 | 0.99 | LIPG (0.42) | LIPGPPARAFUT7THRATHRB | |
| SCHEMBL27495854 | 0.88 | LIPG (0.45) | LIPGPPARATHRATHRBNR1H2 | |
| SCHEMBL7143805 | 0.86 | LIPG (0.41) | LIPGPPARAFUT7THRATHRB | |
| Ammonia Solution, Strong SCHEMBL27553670 | 0.86 | LIPG (0.44) | LIPGPPARATHRATHRBNR1H2 | |
| Hydrochloric Acid SCHEMBL28880990 | 0.85 | LIPG (0.53) | LIPGPPARATHRATHRBNR1H2 | |
| Hydrochloric Acid SCHEMBL2898929 | 0.85 | LIPG (0.53) | LIPGPPARATHRATHRBNR1H2 | |
| Hydrochloric Acid SCHEMBL5072856 | 0.85 | LIPG (0.53) | LIPGPPARATHRATHRBNR1H2 | |
| Hydrochloric Acid SCHEMBL11542002 | 0.85 | LIPG (0.53) | LIPGPPARATHRATHRBNR1H2 | |
| Hydrochloric Acid SCHEMBL28853938 | 0.85 | LIPG (0.53) | LIPGPPARATHRATHRBNR1H2 | |
| Sulfuric Acid SCHEMBL27540444 | 0.85 | LIPG (0.45) | LIPGPPARATHRATHRBNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709980-A1 | Emanation device | Reckitt Benckiser (UK) LIMITED (GB) | 2006-10-11 | — | — | EP | disclosed |