Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | PRKCB | P05771 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCH | P24723 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20314605 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL12924148 | 0.97 | ALDH1A1 (0.46) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL12924142 | 0.97 | ALDH1A1 (0.46) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL20314604 | 0.97 | ALDH1A1 (0.46) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL18775170 | 0.96 | ALDH1A1 (0.43) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL1883570 | 0.96 | ALDH1A1 (0.43) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL16411964 | 0.96 | ALDH1A1 (0.43) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL20314606 | 0.94 | ALDH1A1 (0.44) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL12924151 | 0.94 | ALDH1A1 (0.44) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL9678153 | 0.94 | ALDH1A1 (0.44) | ALDH1A1HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708999-A1 | BRONCHORELAXING COMPOUNDS | RESPIRATORIUS AB (SE) | 2006-10-11 | — | — | EP | disclosed |
| US-20060040919-A1 | Bronchorelaxing compounds | RESPIRATORIUS AB (SE) | 2006-02-23 | — | — | US | disclosed |
| WO-2005070887-A1 | BRONCHORELAXING COMPOUNDS | RESPIRATORIUS AB (SE) | 2005-08-04 | — | — | WO | disclosed |
| US-20050165004-A1 | Bronchorelaxing compounds | RESPIRATORIUS AB (SE) | 2005-07-28 | — | — | US | disclosed |
| US-5679699-A | ANTIISCHEMIC AGENTS, HEART RATE LOWERING AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1997-10-21 | — | — | US | disclosed |
| US-5547967-A | HYPOTENSIVE AGENT, ANTIISCHEMIC AGENT | KALI-CHEMIE PHARMA GMBH (DE) | 1996-08-20 | — | — | US | disclosed |
| US-5474988-A | Analgesics, antiinflammatory agents | KALI-CHEMIE PHARMA GMBH (DE) | 1995-12-12 | — | — | US | disclosed |
| US-5332733-A | Antiallergens, antiinflammatory | KALI-CHEMIE PHARMA GMBH (DE) | 1994-07-26 | — | — | US | disclosed |
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |
| US-5283243-A | Anti-inflammatory, anti-allergic, hypotensive and vasodilating agents | KALI-CHEMIE PHARMA GMBH (DE) | 1994-02-01 | — | — | US | disclosed |
| US-5272143-A | 6-oxoazepinoindole compounds, and pharmaceutical compositions containing them | KALI-CHEMIE PHARMA GMBH (DE) | 1993-12-21 | — | — | US | disclosed |
| CN-1069733-A | 6-OXO-AZA * INDOLES, PROCESS FOR THEIR PRODUCTION, INTERMEDIATE PRODUCTS AND PHARMACEUTICAL APPLICATIONS | KALI CHEMIE PHARMA GMBH (DE) | 1993-03-10 | — | — | CN | disclosed |
| US-4695566-A | 3-aminocarbonylmethoxy-5-phenylpyrazole compounds, antiarrythmic compositions containing them, and intermediates in their preparation | KALI-CHEMIE PHARMA GMBH (DE) | 1987-09-22 | — | — | US | disclosed |
| US-4576632-A | HERBICIDES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-03-18 | — | — | US | disclosed |
| US-4494979-A | HERBICIDES;PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-22 | — | — | US | disclosed |
| EP-0071441-A2 | Benzofuran sulfamates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165004-A1 | Bronchorelaxing compounds | GPR6, CHRM3, NR1H3 | ALDH1A1 2197/4885HTT 3933/4885MEN1 1409/4885 |
| US-20060040919-A1 | Bronchorelaxing compounds | CHRM3, GPR3, CHRM2 | ALDH1A1 2507/4885HTT 3953/4885MEN1 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.