Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709087 | 0.99 | HRH3 (0.71) | HRH3SIGMAR1KDM4EALDH1A1KMT2A | |
| SCHEMBL22813625 | 0.90 | HRH3 (0.83) | HRH3SIGMAR1LTA4HDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL10352286 | 0.88 | HRH3 (0.78) | HRH3SIGMAR1KDM4EALDH1A1KMT2A | |
| SCHEMBL10669091 | 0.84 | HRH3 (1.00) | HRH3SIGMAR1LTA4H | |
| SCHEMBL11778348 | 0.84 | CHRM2 (0.63) | HRH3SIGMAR1 | |
| SCHEMBL17294993 | 0.83 | HRH3 (0.97) | HRH3SIGMAR1LTA4H | |
| SCHEMBL2451796 | 0.80 | SIGMAR1 (0.61) | HRH3SIGMAR1LTA4HABCB1 | |
| SCHEMBL20233625 | 0.80 | HRH3 (0.70) | HRH3SIGMAR1DRD2 | |
| SCHEMBL492156 | 0.80 | HRH3 (0.97) | HRH3SIGMAR1LTA4H | |
| SCHEMBL2097710 | 0.79 | SIGMAR1 (0.63) | HRH3SIGMAR1LTA4HABCB1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1717233-A1 | Histamine H3-receptor ligands and their therapeutic application | BIOPROJET (FR) | 2006-11-02 | — | — | EP | disclosed |