Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Inositol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL7707543 | 0.96 | BLM (0.56) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL5789307 | 0.96 | BLM (0.56) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL727085 | 0.96 | BLM (0.56) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL28174334 | 0.96 | BLM (0.56) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL1275425 | 0.96 | BLM (0.56) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL4412209 | 0.91 | ALOX15 (0.50) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL5800546 | 0.91 | ALOX15 (0.50) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL17545226 | 0.91 | ALOX15 (0.50) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL22654330 | 0.91 | ALOX15 (0.50) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL22654329 | 0.91 | ALOX15 (0.50) | BLMKMT2AALOX15PMP22GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716238-B1 | METHOD FOR MODIFYING GENE EXPRESSION OF A PHYTOPATHOGENIC FUNGUS | BAYER SAS (FR) | 2017-12-06 | — | — | EP | disclosed |
| EP-1716238-A1 | METHOD FOR MODIFYING GENE EXPRESSION OF A PHYTOPATHOGENIC FUNGUS | Bayer CropScience S.A. (FR) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005071091-A1 | METHOD FOR MODIFYING GENE EXPRESSION OF A PHYTOPATHOGENIC FUNGUS | BAYER CROPSCIENCE SA (FR) | 2005-08-04 | — | — | WO | disclosed |