Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL7707543 | 1.00 | BLM (0.56) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL1275425 | 1.00 | BLM (0.56) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL5789307 | 1.00 | BLM (0.56) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL28174334 | 1.00 | BLM (0.56) | BLMKMT2AALOX15PMP22GRM8 | |
| Inositol SCHEMBL5709159 | 0.96 | BLM (0.51) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL4412209 | 0.95 | ALOX15 (0.50) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL5800546 | 0.95 | ALOX15 (0.50) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL17545226 | 0.95 | ALOX15 (0.50) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL22654330 | 0.95 | ALOX15 (0.50) | BLMKMT2AALOX15PMP22GRM8 | |
| Glutamine SCHEMBL22654329 | 0.95 | ALOX15 (0.50) | BLMKMT2AALOX15PMP22GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1889974-A | Oligopeptides as coating material for medical products | HEMOTEQ GMBH (DE) | 2007-01-03 | — | — | CN | claimed |
| US-20240207376-A1 | Compositions and Methods for Treating Celiac Sprue Disease | UNIVERSITY OF WASHINGTON | 2024-06-27 | — | — | US | disclosed |
| WO-2024112863-A1 | COMPOSITIONS AND METHODS TO INCREASE FEED EFFICIENCY IN ANIMALS | CHURCH & DWIGHT CO., INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2024105276-A1 | COMBINATION OF POLYAMINE PATHWAY INHIBITOR DRUG AND PROLINE/ARGININE DIET RESTRICTION | Universität Zürich (CH) | 2024-05-23 | — | — | WO | disclosed |
| CN-117737236-A | Application of PQLC2 gene in preparation of medicines for treating liver cancer and diagnostic kit | 北京化工大学 | 2024-03-22 | — | — | CN | disclosed |
| US-20240058246-A1 | LIPO-AMINO ACID ALKYL ESTERS AS SPF BOOSTERS | PRODOTTI GIANNI S.R.L. (IT) | 2024-02-22 | — | — | US | disclosed |
| US-11793738-B2 | Lipo-amino acid alkyl esters as SPF boosters | PRODOTTI GIANNI S.R.L. (IT) | 2023-10-24 | — | — | US | disclosed |
| CN-116445503-A | Cryptomeria fortunei CfNAC1 gene and expression protein and application thereof | 南京林业大学 | 2023-07-18 | — | — | CN | disclosed |
| EP-4023243-A2 | COMPOSITIONS AND METHODS FOR TREATING CELIAC SPRUE DISEASE | University of Washington through its Center for Commercialization (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-4011357-A1 | LIPO-AMINO ACID ALKYL ESTERS AS SPF BOOSTERS | Prodotti Gianni S.r.l. (IT) | 2022-06-15 | — | — | EP | disclosed |
| US-5627064-A | POLYNUCLEOTIDE SEQUENCES AND POLYPEPTIDES CODES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0690876-A1 | PROTEIN KINASES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1996-01-10 | — | — | EP | disclosed |
| WO-1995019993-A1 | PROTEIN KINASES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1995-07-27 | — | — | WO | disclosed |
| EP-0632832-A1 | PROTEIN KINASES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0594710-A4 | TYROSINE KINASE. | SALK INST FOR BIOLOGICAL STUDI (US) | 1994-11-02 | — | — | EP | disclosed |
| WO-1994017189-A2 | PROTEIN KINASES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1994-08-04 | — | — | WO | disclosed |
| EP-0594710-A1 | TYROSINE KINASE | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1994-05-04 | — | — | EP | disclosed |
| EP-0546108-A4 | PRO-DRUGS FOR CCK ANTAGONISTS | — | 1993-09-22 | — | — | EP | disclosed |
| EP-0546108-A1 | PRO-DRUGS FOR CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1993001205-A1 | TYROSINE KINASE | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1993-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11793738-B2 | Lipo-amino acid alkyl esters as SPF boosters | SLC43A1, CUTA, AADAT | BLM 1366/4885KMT2A 1621/4885ALOX15 51/4885 |
| US-20240058246-A1 | LIPO-AMINO ACID ALKYL ESTERS AS SPF BOOSTERS | SLC43A1, CUTA, AADAT | BLM 1366/4885KMT2A 1621/4885ALOX15 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.