Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL247596 | 0.89 | TSHR (0.64) | DAOTSHRNAPRTMAPK1CES2 | |
| Benzoic Acid SCHEMBL28740642 | 0.87 | TSHR (0.52) | DAOTSHRNAPRTMAPK1CES2 | |
| Benzoic Acid SCHEMBL14955492 | 0.85 | TSHR (0.54) | DAOTSHRNAPRTMAPK1CES2 | |
| Benzoic Acid SCHEMBL561340 | 0.84 | TSHR (0.52) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11508647 | 0.83 | TSHR (0.56) | DAOTSHRNAPRTMAPK1CES2 | |
| Benzoic Acid SCHEMBL28596822 | 0.83 | TSHR (0.56) | DAOTSHRNAPRTMAPK1CES2 | |
| Benzoic Acid SCHEMBL2020361 | 0.83 | TSHR (0.56) | DAOTSHRNAPRTMAPK1CES2 | |
| Benzoic Acid SCHEMBL18918947 | 0.83 | TSHR (0.56) | DAOTSHRNAPRTMAPK1CES2 | |
| Benzoic Acid SCHEMBL27545785 | 0.82 | TSHR (0.50) | DAOTSHRNAPRTMAPK1CES2 | |
| Benzoic Acid SCHEMBL28673610 | 0.81 | TSHR (0.54) | DAOTSHRNAPRTMAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601224-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2018-09-19 | — | — | EP | disclosed |
| EP-2601224-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2013-06-12 | — | — | EP | disclosed |
| US-20130131290-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2013-05-23 | — | — | US | disclosed |
| WO-2012017040-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2012-02-09 | — | — | WO | disclosed |