Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436029 | 0.81 | — | — | |
| SCHEMBL6836741 | 0.74 | CHRM2 (0.41) | CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL1395058 | 0.73 | PDK1 (0.39) | CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL2846269 | 0.71 | PDK1 (0.38) | CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL981080 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL30766147 | 0.70 | PTPN1 (0.33) | — | |
| SCHEMBL11802868 | 0.69 | — | — | |
| SCHEMBL11025614 | 0.68 | USP2 (0.34) | — | |
| SCHEMBL9450309 | 0.67 | CHRM2 (0.45) | THRBCHRM2CHRM4CHRM5CHRM3 | |
| Oxirane SCHEMBL11531139 | 0.67 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458327-B1 | DEVICE FOR DENTAL APPLICATIONS | KANCA JOHN III (US) | 2006-12-06 | — | — | EP | disclosed |