SCHEMBL5709346

SCHEMBL5709346

CC(C)(C)[Si](C)(C)OCCCC1(c2ccc(Cl)cc2)CCc2cc(F)c(F)cc21

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BCHE P06276 6/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5709368 0.88 BCHE (0.40) BCHE
SCHEMBL5709473 0.84 BCHE (0.32) BCHE
SCHEMBL5709418 0.82 BCHE (0.45) BCHE
SCHEMBL5709355 0.79 BCHE (0.36) BCHE
SCHEMBL5709380 0.78 BCHE (0.36) BCHE
SCHEMBL5709370 0.76 SLC6A4 (0.40) BCHE
SCHEMBL5709334 0.71 BCHE (0.40) BCHE
Hydrochloric Acid SCHEMBL5709488 0.69 BCHE (0.40) BCHE
SCHEMBL5709351 0.69 BCHE (0.43) BCHE
SCHEMBL17748895 0.68 BACE1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1727785-A1 PHENYL INDAN DERIVATIVES H.Lundbeck A/S (DK) 2006-12-06 EP disclosed
WO-2005087708-A1 PHENYL INDAN DERIVATIVES H. LUNDBECK A/S (DK) 2005-09-22 WO disclosed