Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709473 | 0.91 | BCHE (0.32) | BCHEKDM1A | |
| SCHEMBL5709346 | 0.88 | BCHE (0.35) | BCHE | |
| SCHEMBL5709418 | 0.86 | BCHE (0.45) | BCHESLC6A4 | |
| SCHEMBL5709388 | 0.78 | BCHE (0.42) | BCHEKDM1AHTR1ADRD2DRD1 | |
| SCHEMBL5709370 | 0.78 | SLC6A4 (0.40) | BCHESLC6A2SLC6A4 | |
| SCHEMBL17748895 | 0.70 | BACE1 (0.33) | KDM1A | |
| SCHEMBL5709447 | 0.70 | BCHE (0.42) | BCHEKDM1ADRD2 | |
| SCHEMBL5709350 | 0.69 | KDM1A (0.38) | BCHEKDM1ADRD2SLC6A2HTR2A | |
| SCHEMBL5709526 | 0.69 | BCHE (0.47) | BCHESLC6A4 | |
| SCHEMBL5709328 | 0.69 | KDM1A (0.37) | BCHEKDM1ADRD2SLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |