Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709355 | 0.89 | BCHE (0.36) | BCHESLC6A4KDM1A | |
| SCHEMBL5709349 | 0.87 | BCHE (0.48) | BCHECYP17A1CYP3A4CYP11B2SLC6A4 | |
| SCHEMBL5709380 | 0.77 | BCHE (0.36) | BCHECYP17A1CYP3A4CYP11B2 | |
| SCHEMBL5709447 | 0.77 | BCHE (0.42) | BCHECYP17A1CYP3A4CYP11B2KDM1A | |
| SCHEMBL5709423 | 0.75 | BCHE (0.47) | BCHECYP17A1CYP3A4CYP11B2KDM1A | |
| SCHEMBL5709388 | 0.72 | BCHE (0.42) | BCHESLC6A4KDM1A | |
| SCHEMBL5709350 | 0.70 | KDM1A (0.38) | BCHEKDM1A | |
| SCHEMBL24750180 | 0.69 | BCHE (0.63) | BCHECYP3A4SLC6A4 | |
| SCHEMBL5709346 | 0.69 | BCHE (0.35) | BCHE | |
| SCHEMBL5709334 | 0.69 | BCHE (0.40) | BCHESLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |