Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709389 | 1.00 | KDM1A (0.39) | KDM1ACCR1OPRM1EPHX2HTR2A | |
| SCHEMBL5709491 | 1.00 | KDM1A (0.39) | KDM1ACCR1OPRM1EPHX2HTR2A | |
| SCHEMBL5709333 | 0.82 | KDM1A (0.43) | KDM1AHTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL5709421 | 0.82 | KDM1A (0.43) | KDM1AHTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL5709521 | 0.81 | KDM1A (0.42) | KDM1ACCR1HTR2AHTR2CSLC6A2 | |
| SCHEMBL5709387 | 0.81 | KDM1A (0.42) | KDM1ACCR1HTR2AHTR2CSLC6A2 | |
| SCHEMBL5709345 | 0.80 | KCNA5 (0.42) | KDM1ACCR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5709415 | 0.77 | KCNK2 (0.41) | KDM1AEPHX2SLC6A9 | |
| SCHEMBL5709340 | 0.75 | KDM1A (0.43) | KDM1ACCR1SIGMAR1 | |
| SCHEMBL5709361 | 0.73 | HSD11B1 (0.43) | KDM1ASLC6A2SLC6A4SLC6A3SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |