Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 8/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709371 | 0.88 | KDM1A (0.47) | KDM1ASIGMAR1MAOBMAOAHRH3 | |
| SCHEMBL5709343 | 0.87 | KDM1A (0.46) | KDM1ASIGMAR1MAOBMAOAHRH3 | |
| SCHEMBL5709377 | 0.84 | FFAR1 (0.44) | KDM1ASIGMAR1MAOBMAOA | |
| SCHEMBL5709345 | 0.83 | KCNA5 (0.42) | KDM1ACCR1AR | |
| SCHEMBL5709462 | 0.82 | KDM1A (0.45) | KDM1ASIGMAR1MAOBMAOAHRH3 | |
| SCHEMBL27660688 | 0.81 | KDM1A (0.47) | KDM1ACCR1SIGMAR1MAOBMAOA | |
| SCHEMBL5709474 | 0.77 | AR (0.40) | KDM1AMAOBHRH3AR | |
| SCHEMBL5709389 | 0.75 | KDM1A (0.39) | KDM1ACCR1SIGMAR1 | |
| SCHEMBL5709358 | 0.75 | KDM1A (0.39) | KDM1ACCR1SIGMAR1 | |
| SCHEMBL5709491 | 0.75 | KDM1A (0.39) | KDM1ACCR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |