Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709383 | 0.89 | KCNA5 (0.44) | KCNA5SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL5709406 | 0.86 | KCNA5 (0.43) | KCNA5SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL5709345 | 0.85 | KCNA5 (0.42) | KCNA5SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL5709474 | 0.83 | AR (0.40) | KCNA5ALDH1A1SMN1; SMN2ARKDM1A | |
| SCHEMBL5709523 | 0.83 | KCNA5 (0.45) | KCNA5SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL5709343 | 0.82 | KDM1A (0.46) | SLC6A2SLC6A3SMN1; SMN2ARKDM1A | |
| SCHEMBL5709521 | 0.79 | KDM1A (0.42) | SLC6A2SLC6A4SLC6A3KDM1ADRD2 | |
| SCHEMBL5709387 | 0.79 | KDM1A (0.42) | SLC6A2SLC6A4SLC6A3KDM1ADRD2 | |
| SCHEMBL5709440 | 0.79 | BCHE (0.41) | KCNA5ALDH1A1SMN1; SMN2ARHSD17B3 | |
| SCHEMBL5709486 | 0.79 | BCHE (0.41) | KCNA5ALDH1A1SMN1; SMN2ARHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |