Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709523 | 0.89 | KCNA5 (0.45) | KCNA5ALDH1A1SMN1; SMN2ARHSD17B3 | |
| SCHEMBL5709381 | 0.86 | KCNA5 (0.44) | KCNA5ALDH1A1SMN1; SMN2ARHSD17B3 | |
| SCHEMBL5709383 | 0.85 | KCNA5 (0.44) | KCNA5ALDH1A1SMN1; SMN2ARHSD17B3 | |
| SCHEMBL5709377 | 0.84 | FFAR1 (0.44) | FFAR4 | |
| SCHEMBL5709374 | 0.82 | SLC6A2 (0.47) | KCNA5ALDH1A1SMN1; SMN2ARSLC6A2 | |
| SCHEMBL5709440 | 0.81 | BCHE (0.41) | KCNA5ALDH1A1SMN1; SMN2ARHSD17B3 | |
| SCHEMBL5709434 | 0.81 | BCHE (0.41) | KCNA5ALDH1A1SMN1; SMN2ARHSD17B3 | |
| SCHEMBL5709489 | 0.81 | BCHE (0.41) | KCNA5ALDH1A1SMN1; SMN2ARHSD17B3 | |
| SCHEMBL5709486 | 0.81 | BCHE (0.41) | KCNA5ALDH1A1SMN1; SMN2ARHSD17B3 | |
| SCHEMBL5709345 | 0.81 | KCNA5 (0.42) | KCNA5ALDH1A1SMN1; SMN2ARHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |