Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709462 | 0.90 | KDM1A (0.45) | ARKDM1ARAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL5709343 | 0.89 | KDM1A (0.46) | ARKDM1ARAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL5709523 | 0.85 | KCNA5 (0.45) | ARKCNA5RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5709377 | 0.85 | FFAR1 (0.44) | KDM1AMRGPRX4FFAR1MAOBRXRA | |
| SCHEMBL5709381 | 0.83 | KCNA5 (0.44) | ARKDM1AKCNA5SMN1; SMN2ALDH1A1 | |
| SCHEMBL5709371 | 0.81 | KDM1A (0.47) | ARKDM1AMAOBHRH3 | |
| SCHEMBL5709406 | 0.80 | KCNA5 (0.43) | ARKCNA5SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL5709374 | 0.79 | SLC6A2 (0.47) | ARKDM1AKCNA5SMN1; SMN2ALDH1A1 | |
| SCHEMBL5709426 | 0.78 | ALDH1A1 (0.43) | KCNA5RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5709477 | 0.78 | KDM1A (0.38) | ARKDM1AKCNA5RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |