Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 11/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709433 | 1.00 | SLC6A9 (0.47) | SLC6A9BCHESRD5A1SRD5A2KDM1A | |
| SCHEMBL468506 | 0.93 | SLC6A9 (0.43) | SLC6A9BCHESRD5A1SRD5A2KDM1A | |
| Hydrochloric Acid SCHEMBL6169128 | 0.92 | SLC6A9 (0.43) | SLC6A9BCHESRD5A1SRD5A2KDM1A | |
| SCHEMBL5709422 | 0.91 | SLC6A9 (0.42) | SLC6A9BCHE | |
| SCHEMBL5709480 | 0.90 | UTS2R (0.45) | SLC6A9KDM1AALDH1A1UTS2R | |
| SCHEMBL5709332 | 0.83 | UTS2R (0.39) | SLC6A9BCHEUTS2R | |
| SCHEMBL5709334 | 0.82 | BCHE (0.40) | SLC6A9BCHE | |
| SCHEMBL5709478 | 0.81 | BCHE (0.42) | SLC6A9BCHEALDH1A1UTS2R | |
| SCHEMBL468350 | 0.81 | BCHE (0.44) | SLC6A9BCHESRD5A1SRD5A2KDM1A | |
| SCHEMBL468349 | 0.81 | BCHE (0.44) | SLC6A9BCHESRD5A1SRD5A2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | claimed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | claimed |
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |