Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709480 | 0.87 | UTS2R (0.45) | SLC6A9UTS2RALDH1A1SMN1; SMN2KCNA5 | |
| SCHEMBL468506 | 0.87 | SLC6A9 (0.43) | BCHESLC6A9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6169128 | 0.86 | SLC6A9 (0.43) | BCHESLC6A9ALDH1A1 | |
| SCHEMBL5709332 | 0.83 | UTS2R (0.39) | BCHESLC6A9UTS2RKCNA5 | |
| Hydrochloric Acid SCHEMBL5709357 | 0.83 | CYP3A4 (0.41) | BCHECYP3A4HSD17B3ALDH1A1SMN1; SMN2 | |
| SCHEMBL30130487 | 0.81 | SLC6A4 (0.50) | — | |
| SCHEMBL3399464 | 0.81 | SLC6A4 (0.50) | — | |
| SCHEMBL5709384 | 0.81 | SLC6A9 (0.47) | BCHESLC6A9UTS2RALDH1A1 | |
| SCHEMBL5709433 | 0.81 | SLC6A9 (0.47) | BCHESLC6A9UTS2RALDH1A1 | |
| SCHEMBL5709334 | 0.80 | BCHE (0.40) | BCHESLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | claimed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | claimed |
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |