Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 8/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | DRD5 | P21918 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709447 | 0.90 | BCHE (0.42) | BCHEKDM1ADRD2PSEN1PSEN2 | |
| SCHEMBL5709328 | 0.87 | KDM1A (0.37) | BCHEKDM1ADRD2SLC6A2HTR2A | |
| SCHEMBL5709380 | 0.85 | BCHE (0.36) | BCHEDRD2PSEN1PSEN2APH1B | |
| SCHEMBL5709521 | 0.84 | KDM1A (0.42) | KDM1ADRD2SLC6A2HTR2ASLC6A4 | |
| SCHEMBL5709387 | 0.84 | KDM1A (0.42) | KDM1ADRD2SLC6A2HTR2ASLC6A4 | |
| SCHEMBL5709423 | 0.83 | BCHE (0.47) | BCHEKDM1A | |
| SCHEMBL5709368 | 0.78 | BCHE (0.40) | BCHEKDM1ADRD2HTR1ADRD1 | |
| SCHEMBL5709526 | 0.78 | BCHE (0.47) | BCHESLC6A4LMNA | |
| SCHEMBL5709421 | 0.76 | KDM1A (0.43) | BCHEKDM1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL5709333 | 0.76 | KDM1A (0.43) | BCHEKDM1ASLC6A2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |