Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 5/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709388 | 0.90 | BCHE (0.42) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5709423 | 0.87 | BCHE (0.47) | BCHEKDM1ACYP17A1CYP3A4CYP11B2 | |
| SCHEMBL5709349 | 0.85 | BCHE (0.48) | BCHEKDM1ACYP17A1CYP3A4CYP11B2 | |
| SCHEMBL5709328 | 0.79 | KDM1A (0.37) | BCHEDRD2KDM1A | |
| SCHEMBL5709380 | 0.79 | BCHE (0.36) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5709355 | 0.77 | BCHE (0.36) | BCHEDRD2KDM1A | |
| SCHEMBL5709350 | 0.77 | KDM1A (0.38) | BCHEDRD2KDM1A | |
| SCHEMBL5709351 | 0.77 | BCHE (0.43) | BCHEKDM1ACYP17A1CYP3A4CYP11B2 | |
| SCHEMBL5709387 | 0.75 | KDM1A (0.42) | DRD2KDM1A | |
| SCHEMBL5709521 | 0.75 | KDM1A (0.42) | DRD2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |