Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709523 | 0.93 | KCNA5 (0.45) | SLC6A2SLC6A4SLC6A3ARUTS2R | |
| SCHEMBL5709426 | 0.87 | ALDH1A1 (0.43) | SLC6A2SLC6A4SLC6A3UTS2RALDH1A1 | |
| SCHEMBL27660700 | 0.86 | HSD11B1 (0.42) | ALDH1A1KDM1AHSD11B1 | |
| SCHEMBL27680729 | 0.86 | HSD11B1 (0.42) | ALDH1A1KDM1AHSD11B1 | |
| SCHEMBL5709364 | 0.86 | HSD11B1 (0.42) | ALDH1A1KDM1AHSD11B1 | |
| SCHEMBL5709480 | 0.84 | UTS2R (0.45) | SLC6A2SLC6A4SLC6A3ARUTS2R | |
| SCHEMBL5709379 | 0.82 | HSD11B1 (0.39) | ARALDH1A1HSD11B1 | |
| SCHEMBL5709459 | 0.82 | HSD11B1 (0.39) | ARALDH1A1HSD11B1 | |
| SCHEMBL27680727 | 0.82 | HSD11B1 (0.39) | ARALDH1A1HSD11B1 | |
| SCHEMBL5709378 | 0.82 | HSD11B1 (0.41) | ALDH1A1DRD2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |