Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709515 | 0.94 | CYP1A2 (0.45) | MAPTPOLBCXCR1CYP1A2CYP2D6 | |
| SCHEMBL5709463 | 0.84 | POLB (0.45) | POLBCXCR1NOTUMDRD2DRD4 | |
| SCHEMBL5709438 | 0.80 | POLB (0.47) | MAPTPOLBCXCR1CYP1A2CYP2D6 | |
| SCHEMBL3605744 | 0.79 | HIF1A (0.44) | MAPTPOLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3605749 | 0.79 | NOTUM (0.44) | MAPTPOLBCXCR1CYP1A2CYP2D6 | |
| SCHEMBL2981428 | 0.79 | MAPT (0.43) | MAPTPOLBCXCR1CYP1A2CYP2D6 | |
| SCHEMBL2981434 | 0.78 | POLB (0.41) | MAPTPOLBCXCR1CYP1A2CYP2D6 | |
| SCHEMBL2175900 | 0.78 | FAAH (0.48) | MAPTPOLBCXCR1CYP1A2CYP2D6 | |
| SCHEMBL5486911 | 0.77 | NOTUM (0.50) | MAPTPOLBCXCR1CYP1A2CYP2D6 | |
| SCHEMBL2981437 | 0.74 | MAPT (0.39) | MAPTPOLBCXCR1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |