Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 13/20 | 0.43 |
| ▸ | DRD4 | P21917 | 13/20 | 0.43 |
| ▸ | DRD3 | P35462 | 13/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709438 | 0.94 | POLB (0.47) | POLBJAK2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5709441 | 0.84 | MAPT (0.45) | POLBHTTSMN1; SMN2DRD2DRD4 | |
| SCHEMBL5709515 | 0.80 | CYP1A2 (0.45) | POLBALDH1A1SMN1; SMN2DRD2DRD4 | |
| SCHEMBL3594360 | 0.79 | DRD2 (0.45) | POLBJAK2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3594357 | 0.79 | USP30 (0.49) | POLBJAK2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2976745 | 0.78 | JAK2 (0.42) | POLBJAK2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2976748 | 0.78 | JAK2 (0.42) | POLBJAK2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2179185 | 0.78 | FAAH (0.47) | POLBJAK2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4311229 | 0.78 | DRD2 (0.45) | POLBJAK2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5477728 | 0.77 | DRD2 (0.54) | POLBJAK2ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |