Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | AHR | P35869 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810426 | 0.84 | KDM4E (0.65) | CTSDKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL28552806 | 0.84 | KMT2A (0.54) | CTSDHSD17B1KMT2AMEN1ALDH1A1 | |
| SCHEMBL966735 | 0.83 | CTSD (0.62) | CA1CA2CTSDKMT2AMEN1 | |
| SCHEMBL5693970 | 0.80 | CA1 (0.71) | CA1CA2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL23716794 | 0.79 | CTSD (0.63) | CA1CA2CTSDKMT2AMEN1 | |
| SCHEMBL28553519 | 0.79 | KMT2A (0.49) | CTSDHSD17B1KMT2AMEN1ALDH1A1 | |
| SCHEMBL808434 | 0.79 | MPO (0.58) | CA1CA2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5709552 | 0.78 | MAPT (0.70) | KMT2AMEN1ALDH1A1CYP3A4POLB | |
| SCHEMBL11806559 | 0.78 | POLB (0.62) | KMT2AMEN1ALDH1A1NPC1POLB | |
| SCHEMBL4189157 | 0.78 | MAPT (0.70) | CA1CA2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060231589-A1 | Hydroxynaphthalenedicarboxylic acid hydrazide and derivatives thereof as well as process for preparing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO | 2006-10-19 | — | — | US | disclosed |
| EP-1712546-A1 | Hydroxynaphthalenedicarboxylic acid hydrazide and derivatives thereof as well as process for preparing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-10-18 | — | — | EP | disclosed |