Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402900 | 0.81 | THRB (0.39) | THRBMEN1KMT2ASHBG | |
| SCHEMBL25959618 | 0.77 | THRB (0.33) | THRBMEN1KMT2ASHBG | |
| SCHEMBL13952341 | 0.74 | THRB (0.41) | THRBMEN1KMT2ASHBG | |
| SCHEMBL13952290 | 0.74 | THRB (0.41) | THRBMEN1KMT2ASHBG | |
| SCHEMBL13952181 | 0.74 | THRB (0.41) | THRBMEN1KMT2ASHBG | |
| SCHEMBL13462490 | 0.74 | THRB (0.41) | THRBMEN1KMT2ASHBG | |
| SCHEMBL24742714 | 0.72 | THRB (0.39) | THRBMEN1KMT2ASHBG | |
| SCHEMBL9154707 | 0.72 | THRB (0.39) | THRBMEN1KMT2ASHBG | |
| SCHEMBL2451853 | 0.72 | THRB (0.39) | THRBMEN1KMT2ASHBG | |
| SCHEMBL9439852 | 0.72 | THRB (0.39) | THRBMEN1KMT2ASHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1712227-A1 | Amino diols useful in the treatment of Alzheimer's disease | Elan Pharmaceuticals, Inc. (US) | 2006-10-18 | — | — | EP | claimed |