Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | GANAB | Q14697 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25959618 | 0.95 | THRB (0.33) | THRBMEN1KMT2ATP53KDM4E | |
| SCHEMBL5709662 | 0.81 | THRB (0.35) | THRBMEN1KMT2ASHBG | |
| SCHEMBL13462490 | 0.79 | THRB (0.41) | THRBMEN1KMT2ASHBG | |
| SCHEMBL13952341 | 0.79 | THRB (0.41) | THRBMEN1KMT2ASHBG | |
| SCHEMBL13952290 | 0.79 | THRB (0.41) | THRBMEN1KMT2ASHBG | |
| SCHEMBL13952181 | 0.79 | THRB (0.41) | THRBMEN1KMT2ASHBG | |
| SCHEMBL4624231 | 0.78 | THRB (0.36) | THRBMEN1KMT2ATP53KDM4E | |
| SCHEMBL24742714 | 0.77 | THRB (0.39) | THRBMEN1KMT2ASHBG | |
| SCHEMBL9154707 | 0.77 | THRB (0.39) | THRBMEN1KMT2ASHBG | |
| SCHEMBL9439852 | 0.77 | THRB (0.39) | THRBMEN1KMT2ASHBGANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322963-A | Reacting alpha-amino aldehyde derivative with silanol derivative in presence of boron trifluoride-ether complex or tin tetrachloride catalyst | JAPAN TOBACCO, INC. (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0523248-A1 | PROCESS FOR PRODUCING $g(a)-AMINO-$g(b),$g(d)-DIOL DERIVATIVE | Japan Tobacco Inc. (JP) | 1993-01-20 | — | — | EP | disclosed |