SCHEMBL5709677

SCHEMBL5709677

CC(C)(C)c1ccc([S+](c2ccc(C(C)(C)C)cc2)c2ccc(C(C)(C)C)cc2)cc1.Cc1ccc(S(=O)(=O)Oc2ccc(OS(=O)(=O)c3ccc(C)cc3)c(S(=O)(=O)[O-])c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
RECQL P46063 1/20 0.46
HSD11B1 P28845 1/20 0.43
HSD17B3 P37058 1/20 0.43
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ENPP1 P22413 5/20 0.40
ENPP3 O14638 4/20 0.40
ENPP2 Q13822 1/20 0.40
PTPN1 P18031 1/20 0.39
HPGD P15428 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ESR1 P03372 1/20 0.38
GAA P10253 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5709630 0.93 KMT2A (0.47) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL5709663 0.88 MEN1 (0.54) KMT2AMEN1ALDH1A1MAPTRECQL
SCHEMBL5709594 0.87 KMT2A (0.44) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL2284374 0.87 MEN1 (0.58) KMT2AMEN1ALDH1A1MAPTRECQL
SCHEMBL5709684 0.86 HSD11B1 (0.43) KMT2AMEN1ALDH1A1MAPTRECQL
SCHEMBL7119951 0.84 GFER (0.48) KMT2AMEN1ALDH1A1MAPTHSD11B1
SCHEMBL6741005 0.84 HSD11B1 (0.43) KMT2AMEN1ALDH1A1MAPTRECQL
SCHEMBL4077812 0.84 KMT2A (0.52) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL5171833 0.84 ALDH1A1 (0.50) KMT2AMEN1ALDH1A1MAPTRECQL
SCHEMBL6744708 0.84 MEN1 (0.47) KMT2AMEN1ALDH1A1MAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1077391-B1 Onium salts, photoacid generators for resist compositions, and patterning process SHINETSU CHEMICAL CO (JP) 2006-09-27 EP disclosed
US-6440634-B1 MICROFABRICATION OF INTEGRATED CIRCUITS, DEEP UV LITHOGRAPHY; PHENYLSULFONATE SALTS OF SULFONIUM OR IODINIUM CATIONS SHIN-ETSU CHEMICAL CO., LTD (JP) 2002-08-27 US disclosed
EP-1077391-A1 Onium salts, photoacid generators for resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-02-21 EP disclosed