SCHEMBL5709705

SCHEMBL5709705

O=C(O)c1ccc(C(=O)O)c(C(=O)OCC(O)(O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.47
CDC25A P30304 1/20 0.41
CDC25B P30305 1/20 0.41
HSD17B10 Q99714 1/20 0.41
POLB P06746 4/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
RAB9A P51151 1/20 0.39
MAPK1 P28482 2/20 0.39
HIF1A Q16665 1/20 0.39
MYC P01106 1/20 0.37
APEX1 P27695 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
TSHR P16473 2/20 0.36
PTPN1 P18031 1/20 0.36
ACE2 Q9BYF1 2/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10408523 0.84 KDM4E (0.45) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL973100 0.83 KDM4E (0.53) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL1104259 0.82 KDM4E (0.43) KDM4ECDC25ACDC25BHSD17B10POLB
Ethylene Glycol SCHEMBL5687572 0.82 KDM4E (0.43) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL11372672 0.82 KDM4E (0.43) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL6900919 0.80 TDP1 (0.50) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL6227901 0.80 HRH3 (0.52) KDM4EHSD17B10ALDH1A1LMNAMYC
SCHEMBL1121797 0.80 KDM4E (0.41) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL2352254 0.79 KDM4E (0.49) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL9417452 0.77 KDM4E (0.47) KDM4ECDC25ACDC25BHSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1115692-A4 PRODUCTION OF IMPROVED POLYMERS VIA THE USE OF STAR CORES SWIG PTY LTD (AU) 2003-04-23 EP claimed
EP-1115692-A1 PRODUCTION OF IMPROVED POLYMERS VIA THE USE OF STAR CORES Swig Pty. Ltd. (AU) 2001-07-18 EP claimed
WO-2000017151-A1 PRODUCTION OF IMPROVED POLYMERS VIA THE USE OF STAR CORES SWIG PTY LTD (AU) 2000-03-30 WO claimed
EP-0391538-B1 CONTINUOUS PRODUCTION OF POLYESTER FILAMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-16 EP claimed
EP-0391538-A2 Continuous production of polyester filaments E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-10 EP claimed
US-4945151-A DYE UNIFORMITY, CHAIN BRANCHING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-07-31 US claimed
EP-1115692-B1 PRODUCTION OF IMPROVED POLYMERS VIA THE USE OF STAR CORES PETRECYCLE PTY LTD (AU) 2006-11-15 EP disclosed
US-6646062-B1 Production of improved polymers via the use of star cores PETRECYCLE PTY LTD (AU) 2003-11-11 US disclosed
EP-1115692-A4 PRODUCTION OF IMPROVED POLYMERS VIA THE USE OF STAR CORES SWIG PTY LTD (AU) 2003-04-23 EP disclosed
US-6413631-B1 OVAL CROSS-SECTION TO IMPROVE DYEABILITY, SOFTNESS, AND SMOOTHNESS E. I. DU PONT DE NEMOURS AND COMPANY 2002-07-02 US disclosed
EP-0783607-B1 IMPROVEMENTS IN PILLOWS AND OTHER FILLED ARTICLES AND IN THEIR FILLING MATERIALS DU PONT (US) 2002-03-20 EP disclosed
EP-1183410-A1 TOW AND PROCESS OF MAKING E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-03-06 EP disclosed
EP-0981658-B1 POLYESTER YARN DU PONT (US) 2001-12-19 EP disclosed
US-5458971-A Bicomponent polyester fiberfill, branched and unbranched; hollow spiral crimp E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-10-17 US disclosed
EP-0391538-B1 CONTINUOUS PRODUCTION OF POLYESTER FILAMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-16 EP disclosed
EP-0391538-A3 CONTINUOUS PRODUCTION OF POLYESTER FILAMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-02-13 EP disclosed
EP-0391538-A2 Continuous production of polyester filaments E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-10 EP disclosed
EP-0391538-A2 Continuous production of polyester filaments E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-10 EP disclosed
US-4945151-A DYE UNIFORMITY, CHAIN BRANCHING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-07-31 US disclosed
US-4945151-A DYE UNIFORMITY, CHAIN BRANCHING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-07-31 US disclosed