SCHEMBL973100

SCHEMBL973100

O=C(O)c1ccc(C(=O)O)c(C(=O)OCCOC(=O)c2cc(C(=O)O)ccc2C(=O)O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
SERPINE1 P05121 2/20 0.49
CDC25A P30304 1/20 0.46
CDC25B P30305 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 3/20 0.44
POLB P06746 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.42
RAB9A P51151 1/20 0.42
TSHR P16473 4/20 0.42
MYC P01106 1/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
TP53 P04637 2/20 0.40
MAPK1 P28482 2/20 0.40
APEX1 P27695 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6900919 0.93 TDP1 (0.50) KDM4ECDC25ACDC25BHSD17B10TDP1
SCHEMBL12126222 0.92 KDM4E (0.46) KDM4ESERPINE1CDC25ACDC25BHSD17B10
SCHEMBL2352254 0.91 KDM4E (0.49) KDM4ESERPINE1CDC25ACDC25BHSD17B10
SCHEMBL17713249 0.90 ALDH1A1 (0.54) KDM4EHSD17B10TDP1POLBL3MBTL1
SCHEMBL10493881 0.89 KDM4E (0.44) KDM4ESERPINE1CDC25ACDC25BHSD17B10
SCHEMBL10939038 0.89 KDM4E (0.44) KDM4ESERPINE1CDC25ACDC25BHSD17B10
SCHEMBL17746781 0.89 KDM4E (0.46) KDM4ESERPINE1CDC25ACDC25BHSD17B10
SCHEMBL10892651 0.88 THRB (0.47) KDM4ESERPINE1CDC25ACDC25BHSD17B10
SCHEMBL10819511 0.88 TSHR (0.51) KDM4ESERPINE1CDC25ACDC25BHSD17B10
SCHEMBL4274180 0.88 KDM4E (0.43) KDM4ESERPINE1CDC25ACDC25BHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799791-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-01-13 EP claimed
US-7994273-B2 Photoactive materials ROLIC AG (CH) 2011-08-09 US claimed
EP-2305632-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP claimed
US-20100272979-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2010-10-28 US claimed
US-7687118-B2 Photocrosslinkable materials ROLIC AG (CH) 2010-03-30 US claimed
US-20080069968-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-03-20 US claimed
EP-1801097-A1 Photocrosslinkable materials Rolic AG (CH) 2007-06-27 EP claimed
EP-1799791-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2007-06-27 EP claimed
EP-1273626-B1 Aqueous resin composition, aqueous coating material containing the composition, coating provided by the material, and metal plate coated with the material TOYO BOSEKI (JP) 2006-05-17 EP claimed
US-7034098-B2 POlyimide, polyamide; liquid crystals, opticsoptics ROLIC AG (CH) 2006-04-25 US claimed
US-7030197-B2 Aqueous resin composition, aqueous coating material containing the composition, coating provided by the material, and metal plate coated with the material TOYO BOSEKI KABUSHIKI KAISHA (JP) 2006-04-18 US claimed
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked ROLIC AG (CH) 2005-12-29 US claimed
EP-1368411-B1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2005-07-06 EP claimed
EP-1525182-A1 PHOTOACTIVE MATERIALS Rolic AG (CH) 2005-04-27 EP claimed
US-20040185215-A1 Photoactive polymer based on polyimides, polyamic acids and esters characterised in that it contains as a side-chain a dendritic block incorporating photoactive groups at its surface; use as orientation layers for liquid crystals and in the construction of unstructured and structured optical elements ROLIC AG (CH) 2004-09-23 US claimed
WO-2004013086-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2004-02-12 WO claimed
EP-1386910-A1 Photoactive materials Rolic AG (CH) 2004-02-04 EP claimed
US-20030083425-A1 Aqueous resin composition, aqueous coating material containing the composition, coating provided by the material, and metal plate coated with the material TOYO BOSEKI KABUSHIKI KAISHA (JP) 2003-05-01 US claimed
EP-1273626-A1 Aqueous resin composition, aqueous coating material containing the composition, coating provided by the material, and metal plate coated with the material Toyo Boseki Kabushiki Kaisha (JP) 2003-01-08 EP claimed
EP-1229066-A1 Photoactive polymer Rolic AG (CH) 2002-08-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked C9, F12, DAO KDM4E 1781/4885SERPINE1 513/4885CDC25A 636/4885
US-20080069968-A1 Photocrosslinkable Materials PARG, VSIR, IGLV6-57 KDM4E 844/4885SERPINE1 1579/4885CDC25A 2337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.