Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | GMNN | O75496 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737262 | 0.81 | CETP (0.39) | GPR84MAPK1MAPTMEN1KMT2A | |
| SCHEMBL5709972 | 0.81 | CETP (0.39) | GPR84MAPK1MAPTMEN1KMT2A | |
| SCHEMBL8737252 | 0.81 | CETP (0.39) | GPR84MAPK1MAPTMEN1KMT2A | |
| SCHEMBL8735262 | 0.81 | CETP (0.39) | GPR84MAPK1MAPTMEN1KMT2A | |
| SCHEMBL29089253 | 0.79 | ACE2 (0.40) | GPR84MAPK1MAPTMEN1KMT2A | |
| SCHEMBL27823126 | 0.76 | CETP (0.35) | MAPK1MEN1KMT2ATSHRCETP | |
| SCHEMBL2553554 | 0.75 | GPR84 (0.43) | GPR84MAPTCETPPPARD | |
| SCHEMBL27813139 | 0.74 | CETP (0.35) | TSHRCETP | |
| SCHEMBL29089246 | 0.74 | CA2 (0.39) | GPR84MAPK1MAPTTSHRCETP | |
| SCHEMBL8736619 | 0.74 | CA2 (0.39) | GPR84MAPK1MAPTTSHRCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179435-B1 | Reversible thermochromic composition having improved light-fastness and product comprising same | PILOT INK CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |