Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.63 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | STS | P08842 | 6/20 | 0.61 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677218 | 1.00 | ALDH1A1 (0.71) | ALDH1A1NPC1MAPTRAB9AGAA | |
| SCHEMBL6244199 | 1.00 | ALDH1A1 (0.71) | ALDH1A1NPC1MAPTRAB9AGAA | |
| SCHEMBL27695864 | 1.00 | ALDH1A1 (0.71) | ALDH1A1NPC1MAPTRAB9AGAA | |
| SCHEMBL7517603 | 1.00 | ALDH1A1 (0.71) | ALDH1A1NPC1MAPTRAB9AGAA | |
| SCHEMBL28506813 | 1.00 | ALDH1A1 (0.71) | ALDH1A1NPC1MAPTRAB9AGAA | |
| SCHEMBL6057260 | 0.98 | ALDH1A1 (0.69) | ALDH1A1NPC1MAPTRAB9AGAA | |
| SCHEMBL17737144 | 0.95 | ALDH1A1 (0.66) | ALDH1A1NPC1MAPTRAB9AGAA | |
| SCHEMBL6057147 | 0.93 | ESR1 (0.72) | ALDH1A1NPC1MAPTRAB9AGAA | |
| SCHEMBL10591672 | 0.91 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL828600 | 0.91 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4865648-A | ELECTRON DONOR DYE; ESTER; PHENOL, CARBOXY ACID, PHOSPHATE ESTER, TRIAZOLE | KITO TSUTOMU (JP) | 1989-09-12 | — | — | US | claimed |
| US-4720301-A | Reversible heat sensitive recording composition | PILOT INK CO., LTD. (JP) | 1988-01-19 | — | — | US | claimed |
| CN-108329746-B | Compounds for reducing background color in color change compositions | 西甘产业股份有限公司 | 2022-08-02 | — | — | CN | disclosed |
| US-11225100-B2 | Tunable directional color transition compositions and methods of making and using the same | SEGAN INDUSTRIES, INC. (US) | 2022-01-18 | — | — | US | disclosed |
| EP-2969582-B1 | COMPOUNDS FOR REDUCING BACKGROUND COLOR IN COLOR CHANGE COMPOSITIONS | SEGAN IND INC (US) | 2021-06-02 | — | — | EP | disclosed |
| US-10570294-B2 | Compounds for reducing background color in color change compositions | SEGAN INDUSTRIES, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20190204280-A1 | Tunable Directional Color Transition Compositions and Methods of Making and Using the Same | SEGAN INDUSTRIES, INC. | 2019-07-04 | — | — | US | disclosed |
| US-20190142713-A1 | Optical Evanescent Color Change Compositions and Methods of Making and Using the Same | SEGAN INDUSTRIES, INC. | 2019-05-16 | — | — | US | disclosed |
| CN-109476946-A | Optics fadout color-changing composition and its method made and used | 西甘产业股份有限公司 | 2019-03-15 | — | — | CN | disclosed |
| EP-3443042-A1 | OPTICAL EVANESCENT COLOR CHANGE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | Segan Industries, Inc. (US) | 2019-02-20 | — | — | EP | disclosed |
| US-10168307-B1 | Tunable directional color transition compositions and methods of making and using the same | SEGAN INDUSTRIES, INC. (US) | 2019-01-01 | — | — | US | disclosed |
| US-20140275381-A1 | COMPOUNDS FOR REDUCING BACKGROUND COLOR IN COLOR CHANGE COMPOSITIONS | SEGAN INDUSTRIES, INC. | 2014-09-18 | — | — | US | disclosed |
| EP-2772523-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION | Kabushiki Kaisha Pilot Corporation (JP) | 2014-09-03 | — | — | EP | disclosed |
| CN-103998569-A | Reversibly thermochromic composition | PILOT CORP | 2014-08-20 | — | — | CN | disclosed |
| US-8569208-B1 | Tunable directional color transition compositions and methods of making and using the same | SEGAN INDUSTRIES, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| EP-1179435-B1 | Reversible thermochromic composition having improved light-fastness and product comprising same | PILOT INK CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| US-6165234-A | FOR IMPARTING REVERSIBLE COLOR CHANGES TO WAXES AND CANDLES WHEN HEATED OR WHEN WAX MELTS OR WHEN THE CANDLE BURNS | KANAKKANATT SEBASTIAN V (US) | 2000-12-26 | — | — | US | disclosed |
| US-4865648-A | ELECTRON DONOR DYE; ESTER; PHENOL, CARBOXY ACID, PHOSPHATE ESTER, TRIAZOLE | KITO TSUTOMU (JP) | 1989-09-12 | — | — | US | disclosed |
| US-4720301-A | Reversible heat sensitive recording composition | PILOT INK CO., LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190142713-A1 | Optical Evanescent Color Change Compositions and Methods of Making and Using the Same | ERCC1, XPA, ERCC5 | ALDH1A1 1999/4885NPC1 627/4885MAPT 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.