Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.72 |
| ▸ | TSHR | P16473 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.72 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057260 | 0.95 | ALDH1A1 (0.69) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL6244199 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL27695864 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL27677218 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL5710046 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7517603 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL28506813 | 0.93 | ALDH1A1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL14029067 | 0.92 | LMNA (0.62) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL15672808 | 0.91 | ESR1 (0.60) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL37476 | 0.91 | ESR1 (0.85) | ESR1TSHRLMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102834420-B | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP. (US) | 2014-10-22 | — | — | CN | claimed |
| US-8569195-B2 | Internal and external donor compounds for olefin polymerization catalysts II | BASF CORPORATION (US) | 2013-10-29 | — | — | US | claimed |
| CN-102834420-A | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP | 2012-12-19 | — | — | CN | claimed |
| CN-1301991-C | Piperidine derivatives, process for preparation thereof, and pharmaceutical composition for alzheimer's disease containing the same | STC NARA CO LTD (KR) | 2007-02-28 | — | — | CN | claimed |
| CN-1571784-A | Piperidine derivatives, process for preparing the same, and pharmaceutical composition for treating alzheimer's disease containing the same | STC NARA CO LTD (KR) | 2005-01-26 | — | — | CN | claimed |
| US-12485157-B2 | Method of treating COVID-19 | PFIZER INC. (US) | 2025-12-02 | — | — | US | disclosed |
| CN-117860750-A | Application of hydrogenated quinibutyl p-chlorobenzoate in preparation of antitumor drugs | 兰州大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-117860750-A | Application of hydrogenated quinibutyl p-chlorobenzoate in preparation of antitumor drugs | 兰州大学 | 2024-04-12 | — | — | CN | disclosed |
| US-20230105838-A1 | Method of Treating COVID-19 | PFIZER INC. (US) | 2023-04-06 | — | — | US | disclosed |
| EP-2782938-B1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF CORP (US) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015129813-A1 | DEUTERATION METHOD AND DEUTERATION CATALYST | 国立大学法人 長崎大学 | 2015-09-03 | — | — | WO | disclosed |
| CN-104540855-A | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE SPA | 2015-04-22 | — | — | CN | disclosed |
| EP-1192196-A1 | PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS | EASTMAN CHEMICAL COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| US-20010051587-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | WESTLAKE LONGVIEW CORPORATION | 2001-12-13 | — | — | US | disclosed |
| US-20010031841-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | WESTLAKE LONGVIEW CORPORATION | 2001-10-18 | — | — | US | disclosed |
| US-20010029286-A1 | Procatalysts, catalyst systems, and use in OLEFIN polymerization | EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE | 2001-10-11 | — | — | US | disclosed |
| US-20010025005-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE | 2001-09-27 | — | — | US | disclosed |
| US-6271321-B1 | CATALYTIC POLYMERIZATION OR COPOLYMERIZATION OF ETHYLENE AND OLEFIN MONOMERS | EASTMAN CHEMICAL COMPANY | 2001-08-07 | — | — | US | disclosed |
| WO-2000075204-A1 | PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS | EASTMAN CHEMICAL COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |
| US-3993437-A | Process for the dyeing of polyamide fibers with sulphur dyestuffs | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12485157-B2 | Method of treating COVID-19 | ACE2, ACE, TMPRSS2 | ESR1 3827/4885TSHR 4625/4885LMNA 2019/4885 |
| US-20230105838-A1 | Method of Treating COVID-19 | ACE2, ACE, TMPRSS2 | ESR1 3827/4885TSHR 4625/4885LMNA 2019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.