Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15987557 | 0.89 | ESR1 (0.54) | ESR1TDP1CYP2C9ALOX15LMNA | |
| SCHEMBL22529043 | 0.87 | ESR1 (0.47) | ESR1TDP1CYP2C9ALOX15LMNA | |
| SCHEMBL9494951 | 0.86 | ESR1 (0.50) | ESR1TDP1CYP2C9ALOX15LMNA | |
| SCHEMBL395463 | 0.84 | ESR1 (0.48) | ESR1TDP1CYP2C9ALOX15LMNA | |
| SCHEMBL10865565 | 0.84 | ESR1 (0.55) | ESR1TDP1CYP2C9ALOX15LMNA | |
| SCHEMBL10610576 | 0.82 | ADRB2 (0.50) | ESR1TDP1CYP2C9ALOX15LMNA | |
| SCHEMBL278254 | 0.79 | ESR1 (0.58) | ESR1TDP1CYP2C9ALOX15LMNA | |
| SCHEMBL6295484 | 0.79 | ESR1 (0.47) | ESR1TDP1CYP2C9ALOX15LMNA | |
| SCHEMBL20622885 | 0.76 | AOC3 (0.38) | TDP1LMNASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL690546 | 0.76 | MAPT (0.38) | ESR1TDP1CYP2C9ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-3954745-B1 | REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME | KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) | 2026-01-07 | — | — | EP | disclosed |
| US-12460099-B2 | Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment | THE PILOT INK CO., LTD. (JP) | 2025-11-04 | — | — | US | disclosed |
| US-12421411-B2 | Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2025-09-23 | — | — | US | disclosed |
| CN-119709173-A | Reversible thermochromic composition and reversible thermochromic microcapsule pigment having the same encapsulated therein | 百乐墨水株式会社 | 2025-03-28 | — | — | CN | disclosed |
| EP-3608386-B1 | REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN | PILOT INK CO LTD (JP) | 2025-02-19 | — | — | EP | disclosed |
| CN-119242290-A | Reversible thermochromic composition and reversible thermochromic microcapsule pigment having the same encapsulated therein | 百乐墨水株式会社 | 2025-01-03 | — | — | CN | disclosed |
| CN-116209725-B | Reversible thermochromic composition and reversible thermochromic microcapsule pigment having the same encapsulated therein | 百乐墨水株式会社 | 2024-12-31 | — | — | CN | disclosed |
| US-12123107-B2 | Reversibly thermochromic composite fiber | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2024-10-22 | — | — | US | disclosed |
| CN-114466751-B | Firing colour pencil lead | 株式会社百乐 | 2024-08-23 | — | — | CN | disclosed |
| US-6946168-B2 | Photochromic phthalein dyes encapsulated in curable oligomers used as coatings on geometric shaped suports as designs | THE PILOT INK CO., LTD. (JP) | 2005-09-20 | — | — | US | disclosed |
| US-6921740-B1 | Electron-receiving compound and thermal recording material | MITSUBISHI PAPER MIILS LTD. (JP) | 2005-07-26 | — | — | US | disclosed |
| US-20040077743-A1 | Photochromic phthalein dyes encapsulated in curable oligomers used as coatings on geometric shaped suports as designs | THE PILOT INK CO., LTD. | 2004-04-22 | — | — | US | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1179435-A1 | Reversible thermochromic composition having improved light-fastness and product comprising same | The Pilot Ink Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5234798-A | Show previously hidden image on exposure to radiant energy | DITTLER BROTHERS, INCORPORATED (US) | 1993-08-10 | — | — | US | disclosed |
| US-4717593-A | Heat-sensitive recording sheet | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-05 | — | — | US | disclosed |
| US-4471073-A | FATTY AMIDES, BISPHENOL COMPOUNDS, DYES | FUJI PHOTO FILM CO., LTD. (JP) | 1984-09-11 | — | — | US | disclosed |
| US-4460626-A | COLORLESS DYE, ORGANIC ACID | FUJI PHOTO FILM CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4415633-A | LAYER CONTAINING CHROMOGEN AND PHENOL OR AROMATIC ACID FUSION-BONDED TO A LOWER-MELTING COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | TYR, SCO2, HBB | ESR1 4366/4885TDP1 1338/4885CYP2C9 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.