Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21982535 | 0.83 | TYR (0.49) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL6057107 | 0.81 | PPARA (0.54) | ALDH1A1TSHRMEN1KMT2ABID | |
| SCHEMBL5710049 | 0.81 | PPARA (0.54) | ALDH1A1TSHRMEN1KMT2ABID | |
| SCHEMBL8922126 | 0.81 | PPARA (0.54) | ALDH1A1TSHRMEN1KMT2ABID | |
| SCHEMBL16041940 | 0.81 | KEAP1 (0.54) | ALDH1A1TSHRPTGDR2MEN1TP53 | |
| SCHEMBL8086397 | 0.80 | CYSLTR2 (0.56) | ALDH1A1BIDMCL1BCL2L1BAK1 | |
| SCHEMBL9559902 | 0.80 | CYSLTR2 (0.56) | ALDH1A1BIDMCL1BCL2L1BAK1 | |
| SCHEMBL573986 | 0.80 | MEN1 (0.55) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL631979 | 0.80 | MEN1 (0.55) | TSHRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL8086516 | 0.80 | CYSLTR2 (0.56) | ALDH1A1BIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4865648-A | ELECTRON DONOR DYE; ESTER; PHENOL, CARBOXY ACID, PHOSPHATE ESTER, TRIAZOLE | KITO TSUTOMU (JP) | 1989-09-12 | — | — | US | claimed |
| US-4720301-A | Reversible heat sensitive recording composition | PILOT INK CO., LTD. (JP) | 1988-01-19 | — | — | US | claimed |
| US-11225100-B2 | Tunable directional color transition compositions and methods of making and using the same | SEGAN INDUSTRIES, INC. (US) | 2022-01-18 | — | — | US | disclosed |
| EP-2969582-B1 | COMPOUNDS FOR REDUCING BACKGROUND COLOR IN COLOR CHANGE COMPOSITIONS | SEGAN IND INC (US) | 2021-06-02 | — | — | EP | disclosed |
| US-10570294-B2 | Compounds for reducing background color in color change compositions | SEGAN INDUSTRIES, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20190204280-A1 | Tunable Directional Color Transition Compositions and Methods of Making and Using the Same | SEGAN INDUSTRIES, INC. | 2019-07-04 | — | — | US | disclosed |
| US-20190142713-A1 | Optical Evanescent Color Change Compositions and Methods of Making and Using the Same | SEGAN INDUSTRIES, INC. | 2019-05-16 | — | — | US | disclosed |
| US-10168307-B1 | Tunable directional color transition compositions and methods of making and using the same | SEGAN INDUSTRIES, INC. (US) | 2019-01-01 | — | — | US | disclosed |
| EP-2772523-B1 | REVERSIBLY THERMOCHROMIC COMPOSITION | PILOT CORPORATION KK (JP) | 2018-11-28 | — | — | EP | disclosed |
| US-9709539-B2 | Tunable directional color transition compositions and methods of making and using the same | SEGAN INDUSTRIES, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20170066931-A1 | Compounds for Reducing Background Color in Color Change Compositions | SEGAN INDUSTRIES, INC. | 2017-03-09 | — | — | US | disclosed |
| US-20140291585-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140275381-A1 | COMPOUNDS FOR REDUCING BACKGROUND COLOR IN COLOR CHANGE COMPOSITIONS | SEGAN INDUSTRIES, INC. | 2014-09-18 | — | — | US | disclosed |
| WO-2014144693-A1 | COMPOUNDS FOR REDUCING BACKGROUND COLOR IN COLOR CHANGE COMPOSITIONS | SEGAN INDUSTRIES, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-2772523-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION | Kabushiki Kaisha Pilot Corporation (JP) | 2014-09-03 | — | — | EP | disclosed |
| US-8569208-B1 | Tunable directional color transition compositions and methods of making and using the same | SEGAN INDUSTRIES, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| EP-1179435-B1 | Reversible thermochromic composition having improved light-fastness and product comprising same | PILOT INK CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| US-4865648-A | ELECTRON DONOR DYE; ESTER; PHENOL, CARBOXY ACID, PHOSPHATE ESTER, TRIAZOLE | KITO TSUTOMU (JP) | 1989-09-12 | — | — | US | disclosed |
| US-4720301-A | Reversible heat sensitive recording composition | PILOT INK CO., LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190142713-A1 | Optical Evanescent Color Change Compositions and Methods of Making and Using the Same | ERCC1, XPA, ERCC5 | ALDH1A1 1999/4885TSHR 3827/4885ACLY 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.