SCHEMBL8922126

SCHEMBL8922126

CCCCCCCCCCCCc1cc(Cl)ccc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.54
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 2/20 0.52
KAT8 Q9H7Z6 4/20 0.50
PPARG P37231 2/20 0.50
KCNK2 O95069 1/20 0.49
RARB P10826 3/20 0.49
RARA P10276 1/20 0.49
RARG P13631 1/20 0.49
HPSE Q9Y251 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
TSHR P16473 1/20 0.47
CASP1 P29466 1/20 0.47
BID P55957 3/20 0.47
MCL1 Q07820 3/20 0.47
BCL2L1 Q07817 2/20 0.47
BAK1 Q16611 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
EP300 Q09472 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5710049 1.00 PPARA (0.54) PPARAKDM4EALDH1A1KAT8PPARG
SCHEMBL6057107 1.00 PPARA (0.54) PPARAKDM4EALDH1A1KAT8PPARG
SCHEMBL15344590 0.94 ALDH1A1 (0.55) PPARAKDM4EALDH1A1KCNK2SMN1; SMN2
SCHEMBL27609036 0.88 FLT1 (0.46) PPARAKDM4EALDH1A1KAT8PPARG
SCHEMBL6057229 0.87 FLT1 (0.57) KDM4EALDH1A1KCNK2SMN1; SMN2TSHR
SCHEMBL7207267 0.86 SIRT1 (0.45) PPARAKDM4EALDH1A1PPARGKCNK2
SCHEMBL28045482 0.84 SIRT1 (0.46) PPARAKDM4EALDH1A1KCNK2MEN1
SCHEMBL8515505 0.84 PPARA (0.56) PPARAALDH1A1KAT8PPARGRARB
SCHEMBL8516008 0.84 PPARA (0.56) PPARAALDH1A1KAT8PPARGRARB
SCHEMBL7271225 0.84 PPARA (0.56) PPARAALDH1A1KAT8PPARGRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5688959-A MULTICOLOR DYE IMAGE AND INFRARED RADIATION ABSORBER WITH 1-HYDROXY-2-N-(5-ALKYLTHIAZOL-2-YL)NAPHTHAMIDE COUPLERS FORMING QUINONE IMINE DYES AGFA-GEVAERT, N.V. (BE) 1997-11-18 US disclosed
US-5030544-A 1-hydroxy-2-n(5-alkyl thiazol 2-yl) naphthamides, form quinone-imine dyes AGFA-GEVAERT, N.V. (BE) 1991-07-09 US disclosed
EP-0176628-B1 PHOTOGRAPHIC COLOUR ELEMENTS AGFA-GEVAERT N.V. (BE) 1987-11-25 EP disclosed
EP-0084692-B1 METHOD OF DISPERSING PHOTOGRAPHIC ADJUVANTS IN A HYDROPHILIC COLLOID COMPOSITION AGFA-GEVAERT N.V. (BE) 1986-06-11 EP disclosed
EP-0176628-A1 Photographic colour elements AGFA-GEVAERT N.V. (BE) 1986-04-09 EP disclosed
US-4430422-A USING 1,3-DIALKYLOXY-2-PROPANOLS AND CARBOXYLIC, PHOSPHORIC OR PHOSPHONIC ESTERS THEREOF AGFA-GEVAERT, N.V. (BE) 1984-02-07 US disclosed
US-4430421-A USING IHYDROXYMETHYL(5,2,1,0(2,6))TRICYCLODECANE, OR CARBOXYLIC, PHOSPHORIC, OR PHOSPHONIC DIESTERS THEREOF AGFA-GEVAERT, N.V. (BE) 1984-02-07 US disclosed
EP-0084694-A1 Method of dispersing photographic adjuvants in hydrophilic colloid compositions AGFA-GEVAERT N.V. (BE) 1983-08-03 EP disclosed
EP-0084692-A2 Method of dispersing photographic adjuvants in a hydrophilic colloid composition AGFA-GEVAERT N.V. (BE) 1983-08-03 EP disclosed