Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | COMT | P21964 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | METAP2 | P50579 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyquinoline SCHEMBL5163066 | 0.90 | MMP2 (0.46) | MMP2CHRM1TSHRCOMTADRA1A | |
| Oxyquinoline SCHEMBL5165934 | 0.80 | MMP2 (0.48) | MMP2CHRM1TSHRCOMTADRA1A | |
| Oxyquinoline SCHEMBL5167730 | 0.78 | MMP2 (0.49) | MMP2CHRM1TSHRCOMTADRA1A | |
| Oxyquinoline SCHEMBL5164457 | 0.78 | MMP2 (0.51) | MMP2CHRM1TSHRCOMTADRA1A | |
| Oxyquinoline SCHEMBL10787641 | 0.75 | TSHR (0.88) | MMP2CHRM1TSHRCOMTADRA1A | |
| Oxyquinoline SCHEMBL29015237 | 0.75 | TSHR (0.88) | MMP2CHRM1TSHRCOMTADRA1A | |
| Oxyquinoline SCHEMBL30367602 | 0.75 | TSHR (0.95) | MMP2CHRM1TSHRCOMTADRA1A | |
| Oxyquinoline SCHEMBL29532359 | 0.75 | TSHR (0.95) | MMP2CHRM1TSHRCOMTADRA1A | |
| SCHEMBL2404902 | 0.75 | KMT2A (0.36) | TSHRKMT2ALMNAALDH1A1NPC1 | |
| Oxyquinoline SCHEMBL543360 | 0.75 | MMP2 (0.95) | MMP2CHRM1TSHRCOMTADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339725-B1 | DNA METHYL TRANSFERASE INHIBITORS | PENN STATE RES FOUND (US) | 2006-11-22 | — | — | EP | disclosed |