Oxyquinoline

Oxyquinoline

SCHEMBL543360

Oc1cccc2cccnc12.Oc1cccc2cccnc12.[BeH2]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.95
TSHR P16473 2/20 0.95
METAP2 P50579 2/20 0.95
CHRM1 P11229 1/20 0.95
COMT P21964 1/20 0.95
ADRA1A P35348 1/20 0.95
METAP1 P53582 1/20 0.95
HDAC8 Q9BY41 1/20 0.95
KDM4E B2RXH2 12/20 0.78
ALOX12 P18054 2/20 0.78
LMNA P02545 2/20 0.66
ALDH1A1 P00352 2/20 0.66
MAPT P10636 3/20 0.58
NFKB1 P19838 2/20 0.58
HTT P42858 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
GMNN O75496 1/20 0.58
TP53 P04637 1/20 0.58
HSP90AA1 P07900 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyquinoline SCHEMBL2059712 1.00 MMP2 (0.95) MMP2TSHRMETAP2CHRM1COMT
Oxyquinoline SCHEMBL37189 0.98 TSHR (1.00) MMP2TSHRMETAP2CHRM1COMT
Oxyquinoline SCHEMBL29716519 0.98 TSHR (1.00) MMP2TSHRMETAP2CHRM1COMT
Oxyquinoline SCHEMBL29365411 0.98 TSHR (1.00) MMP2TSHRMETAP2CHRM1COMT
Oxyquinoline SCHEMBL253313 0.98 TSHR (1.00) MMP2TSHRMETAP2CHRM1COMT
Oxyquinoline SCHEMBL23522696 0.95 TSHR (0.95) MMP2TSHRMETAP2CHRM1COMT
Oxyquinoline SCHEMBL22466317 0.95 TSHR (0.95) MMP2TSHRMETAP2CHRM1COMT
Oxyquinoline SCHEMBL21645991 0.95 TSHR (0.95) MMP2TSHRMETAP2CHRM1COMT
Oxyquinoline SCHEMBL21195162 0.95 TSHR (0.95) MMP2TSHRMETAP2CHRM1COMT
Oxyquinoline SCHEMBL22553419 0.95 TSHR (0.95) MMP2TSHRMETAP2CHRM1COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111087416-B Silicon-containing electron transport material and use thereof 北京夏禾科技有限公司 2024-05-14 CN claimed
CN-112582555-B Organic electroluminescent device 北京夏禾科技有限公司 2023-09-01 CN claimed
CN-112151682-B Organic electroluminescent device comprising hole blocking layer and electron transport layer 夏禾科技(江苏)有限公司 2023-08-22 CN claimed
CN-112390780-B Electron transport material containing nitrogen hetero-spirobifluorene 北京夏禾科技有限公司 2023-06-02 CN claimed
CN-113620885-A Electronic transmission material containing deuterium atom and its application 北京夏禾科技有限公司 2021-11-09 CN claimed
CN-112582555-A Organic electroluminescent device 北京夏禾科技有限公司 2021-03-30 CN claimed
CN-112390780-A Electron transport material containing azaspirobifluorene 北京夏禾科技有限公司 2021-02-23 CN claimed
CN-112151682-A Organic electroluminescent device comprising hole blocking layer and electron transport layer 北京夏禾科技有限公司 2020-12-29 CN claimed
CN-111087416-A Silicon-containing electron transport material and use thereof 北京夏禾科技有限公司 2020-05-01 CN claimed
US-20200131204-A1 SILICON-CONTAINING ELECTRON TRANSPORTING MATERIAL AND ITS APPLICATION Beijing Summer Sprout Technology Co., Ltd. (CN) 2020-04-30 US claimed
US-5516577-A Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 1996-05-14 US claimed
EP-0569827-A2 Organic electroluminescence device IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-18 EP claimed
US-12145954-B2 Silicon-containing electron transporting material and its application Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-11-19 US disclosed
CN-111087416-B Silicon-containing electron transport material and use thereof 北京夏禾科技有限公司 2024-05-14 CN disclosed
CN-112582555-B Organic electroluminescent device 北京夏禾科技有限公司 2023-09-01 CN disclosed
CN-112151682-B Organic electroluminescent device comprising hole blocking layer and electron transport layer 夏禾科技(江苏)有限公司 2023-08-22 CN disclosed
US-5962962-A Method of encapsulating organic electroluminescence device and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 1999-10-05 US disclosed
EP-0781075-A1 METHOD FOR SEALING ORGANIC EL ELEMENT AND ORGANIC EL ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-06-25 EP disclosed
US-5516577-A Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 1996-05-14 US disclosed
EP-0569827-A2 Organic electroluminescence device IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12145954-B2 Silicon-containing electron transporting material and its application SLCO4C1, SLC35E1, SLC2A9 MMP2 2615/4885TSHR 3963/4885METAP2 3783/4885
US-20200131204-A1 SILICON-CONTAINING ELECTRON TRANSPORTING MATERIAL AND ITS APPLICATION SLCO4C1, SLC35E1, SLC2A9 MMP2 2615/4885TSHR 3963/4885METAP2 3783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.