Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5710522 | 0.99 | P2RX7 (0.59) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL5710682 | 0.94 | P2RX7 (0.62) | P2RX7MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5710509 | 0.93 | P2RX7 (0.61) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL5710653 | 0.91 | P2RX7 (0.64) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL5710475 | 0.89 | P2RX7 (0.68) | P2RX7MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5710713 | 0.88 | P2RX7 (0.67) | P2RX7MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5710674 | 0.88 | P2RX7 (0.67) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL5710678 | 0.88 | P2RX7 (0.64) | P2RX7MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5710486 | 0.87 | P2RX7 (0.63) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL5710606 | 0.86 | P2RX7 (0.65) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448195-B1 | N-ADAMANTYLMETHYL DERIVATES AND INTERMEDIATES AS PHARMACEUTICAL COMPOSITIONS AND PROCESSES FOR THEIR PREPARATION | ASTRAZENECA AB (SE) | 2006-11-02 | — | — | EP | claimed |