Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 18/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710678 | 0.96 | P2RX7 (0.64) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL5710475 | 0.96 | P2RX7 (0.68) | P2RX7MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5710486 | 0.95 | P2RX7 (0.63) | P2RX7MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5710713 | 0.95 | P2RX7 (0.67) | P2RX7MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5710674 | 0.95 | P2RX7 (0.67) | P2RX7MEN1ALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5710680 | 0.94 | P2RX7 (0.58) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL5710490 | 0.91 | P2RX7 (0.60) | P2RX7MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5710522 | 0.91 | P2RX7 (0.59) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL5074755 | 0.90 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL5076164 | 0.90 | P2RX7 (0.69) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448195-B1 | N-ADAMANTYLMETHYL DERIVATES AND INTERMEDIATES AS PHARMACEUTICAL COMPOSITIONS AND PROCESSES FOR THEIR PREPARATION | ASTRAZENECA AB (SE) | 2006-11-02 | — | — | EP | claimed |