Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430180 | 0.78 | APLNR (0.56) | CYP2C19APLNRMAPTCYP1A2ALOX15 | |
| SCHEMBL1507147 | 0.71 | — | — | |
| SCHEMBL301495 | 0.71 | — | — | |
| SCHEMBL28490005 | 0.69 | — | — | |
| SCHEMBL2079668 | 0.67 | ABAT (0.48) | CYP2C19APLNRMAPTCYP1A2ALOX15 | |
| SCHEMBL2083101 | 0.67 | ABAT (0.48) | CYP2C19APLNRMAPTCYP1A2ALOX15 | |
| SCHEMBL1839380 | 0.67 | MAPT (0.44) | CYP2C19APLNRMAPTCYP1A2ALOX15 | |
| Benzene SCHEMBL27796799 | 0.67 | AKR1C3 (0.43) | CYP2C19MAPTKDM4EPOLBGAA | |
| SCHEMBL13735122 | 0.67 | CYP2C19 (0.64) | CYP2C19APLNRMAPTCYP1A2ALOX15 | |
| SCHEMBL570687 | 0.64 | APLNR (0.39) | CYP2C19APLNRMAPTCYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018624-A2 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | GENOMATICA, INC. (US) | 2012-02-09 | — | — | WO | disclosed |