SCHEMBL57109

SCHEMBL57109

Oc1ccc(C(F)(F)F)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.84
ESR1 P03372 3/20 0.62
ESR2 Q92731 3/20 0.62
PTGS1 P23219 2/20 0.55
NQO2 P16083 1/20 0.55
PTGS2 P35354 1/20 0.55
LMNA P02545 3/20 0.52
TYR P14679 2/20 0.52
CYP3A4 P08684 2/20 0.52
HPGD P15428 2/20 0.52
TSHR P16473 2/20 0.52
HSD17B10 Q99714 2/20 0.52
AR P10275 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR6 P50406 1/20 0.52
ESRRG P62508 1/20 0.52
SLC6A3 Q01959 1/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL18955872 0.97 KIF11 (0.80) KIF11ESR1ESR2PTGS1NQO2
Potassium SCHEMBL30655561 0.97 KIF11 (0.80) KIF11ESR1ESR2PTGS1NQO2
SCHEMBL28039722 0.97 KIF11 (0.80) KIF11ESR1ESR2PTGS1NQO2
SCHEMBL11756670 0.97 KIF11 (0.80) KIF11ESR1ESR2PTGS1NQO2
Hydrochloric Acid SCHEMBL29242575 0.97 KIF11 (0.80) KIF11ESR1ESR2PTGS1NQO2
SCHEMBL27509291 0.97 KIF11 (0.80) KIF11ESR1ESR2PTGS1NQO2
Cyclohexane SCHEMBL28939325 0.92 KIF11 (0.73) KIF11ESR1ESR2PTGS1NQO2
SCHEMBL12675678 0.92 KIF11 (1.00) KIF11ESR1ESR2PTGS1NQO2
SCHEMBL678508 0.92 KIF11 (1.00) KIF11ESR1ESR2PTGS1NQO2
Phenol SCHEMBL28745379 0.89 KIF11 (0.70) KIF11ESR1ESR2PTGS1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6185 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4690280-A1 AREA SELECTIVE DEPOSITION OF DIELECTRIC FILM ON SILICON CONTAINING SURFACES UTILIZING ALCOHOLS Versum Materials US, LLC (US) 2026-02-11 EP claimed
US-20260001835-A1 PROCESS FOR PREPARING ELECTRON-DEFICIENT OLEFIN MONOMERS AEARDIS LTD. (GB) 2026-01-01 US claimed
EP-4642784-A1 HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 PTC Therapeutics, Inc. (US) 2025-11-05 EP claimed
EP-4642772-A1 NLRP3 INFLAMMASOME INHIBITORS Astrazeneca AB (SE) 2025-11-05 EP claimed
CN-119717393-A Negative phenolic resin composition and preparation method and application thereof 福建泓光半导体材料有限公司 2025-03-28 CN claimed
CN-119706808-A Two-dimensional fluorine-doped carbon nano sheet and preparation and application thereof 中国科学院大连化学物理研究所 2025-03-28 CN claimed
CN-119717394-A Negative mixed phenolic resin composition and preparation method and application thereof 福建泓光半导体材料有限公司 2025-03-28 CN claimed
CN-119695134-A Silicon oxide composite material and preparation method thereof 北京车和家信息技术有限公司 2025-03-25 CN claimed
CN-119613647-A Low-dielectric polybenzoxazine resin and preparation method thereof 中国航空工业集团公司济南特种结构研究所 2025-03-14 CN claimed
CN-119546569-A Method for preparing electron-deficient olefin monomer 埃阿迪斯有限公司 2025-02-28 CN claimed
EP-0080312-A1 The preparation of certain diphenyl ethers especially 5-(4-trifluoromethylphenoxy)- and 5-(2-halo-4-trifluoromethylphenoxy)-2-nitrobenzoic acid and salts and esters and amides ROHM AND HAAS COMPANY (US) 1983-06-01 EP claimed
EP-0013542-B1 ALPHA-PHENOXY PROPIONIC ACID GAMMA-BUTYROLACTONE ESTERS AND THIOESTERS WITH HERBICIDAL ACTIVITY, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AS ACTIVE AGENTS AND THEIR USE CIBA-GEIGY AG (CH) 1982-06-02 EP claimed
EP-0049383-A1 4-Trifluoromethyl-phenyl-(di)thiophosphoric-acid esters, process for preparing them and their use as pesticides BASF Aktiengesellschaft (DE) 1982-04-14 EP claimed
EP-0004447-B1 PREPARATION OF TRIFLUOROMETHYLPHENOLS AND NOVEL TRIFLUOROMETHYLPHENYL BENZYL ETHER INTERMEDIATES ELI LILLY AND COMPANY (US) 1981-12-02 EP claimed
EP-0000542-B1 PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL PHENOLS BAYER AG (DE) 1981-07-15 EP claimed
US-4231787-A 4-(TRIFLUOROMETHYLPHENOXY)PHENOXY-PROPANOLS OR ESTERS ISHIHARA SANGYO KAISHA LTD. (JP) 1980-11-04 US claimed
US-4225731-A Process for the preparation of trifluoromethylphenols BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US claimed
EP-0004447-A2 Preparation of trifluoromethylphenols and novel trifluoromethylphenyl benzyl ether intermediates ELI LILLY AND COMPANY (US) 1979-10-03 EP claimed
US-4126629-A FERTILITY CONTROL MERCK & CO., INC. (US) 1978-11-21 US claimed
US-3953490-A Preparation of (3-trifluoromethylphenoxy)(4-chlorophenyl)acetonitrile MERCK & CO., INC. (US) 1976-04-27 US claimed