Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13448442 | 0.94 | HTT (0.38) | HTT | |
| SCHEMBL12435686 | 0.94 | HTT (0.38) | HTT | |
| SCHEMBL1915246 | 0.85 | HTT (0.50) | HTT | |
| SCHEMBL16884605 | 0.75 | LMNA (0.32) | — | |
| SCHEMBL14127771 | 0.74 | HTT (0.38) | HTT | |
| SCHEMBL8130598 | 0.72 | HTT (0.33) | HTT | |
| SCHEMBL88583 | 0.71 | — | — | |
| SCHEMBL12018255 | 0.71 | — | — | |
| SCHEMBL14087966 | 0.71 | — | — | |
| SCHEMBL12312754 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718632-A1 | PYRIMIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | Sanofi-Aventis (FR) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005075458-A1 | PYRIMIDINE DERIVATIVES AS OREXIN RECEPTORS ANTAGONISTS | SANOFI-AVENTIS (FR) | 2005-08-18 | — | — | WO | disclosed |