Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 15/20 | 0.49 |
| ▸ | ELANE | P08246 | 4/20 | 0.47 |
| ▸ | CTRC | Q99895 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711290 | 0.91 | PRSS8 (0.49) | ELANECTSS | |
| SCHEMBL5711275 | 0.86 | PRSS8 (0.45) | CTSS | |
| SCHEMBL5711349 | 0.86 | CMA1 (0.50) | CMA1CTRC | |
| SCHEMBL7661082 | 0.85 | CMA1 (0.44) | CMA1ELANECTSS | |
| SCHEMBL7668464 | 0.85 | CMA1 (0.44) | CMA1ELANECTRC | |
| SCHEMBL5711189 | 0.85 | CMA1 (0.49) | CMA1CTRC | |
| SCHEMBL5711368 | 0.83 | CMA1 (0.51) | CMA1CTRC | |
| SCHEMBL5711366 | 0.83 | CMA1 (0.58) | CMA1CTRC | |
| SCHEMBL5711273 | 0.82 | CMA1 (0.65) | CMA1ELANECTRC | |
| SCHEMBL5711268 | 0.82 | CMA1 (0.65) | CMA1ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1103560-A1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-05-30 | — | — | EP | disclosed |